Quantcast
Follow us On YouTube Follow us On FaceBook



or
Search Language
Browse
Medical Animations
Medical Animation Titles
Custom Legal Animations
Patient Health Articles
Custom Interactive
Most Recent Uploads
Body Systems/Regions
Anatomy & Physiology
Diseases & Conditions
Diagnostics & Surgery
Cells & Tissues
Cardiovascular System
Digestive System
Integumentary System
Nervous System
Reproductive System
Respiratory System
Back and Spine
Foot and Ankle
Head and Neck
Hip
Knee
Shoulder
Thorax
Medical Specialties
Cancer
Cardiology
Dentistry
Editorial
Neurology/Neurosurgery
Ob/Gyn
Orthopedics
Pediatrics
Account
Administrator Login
Biology: Genetics: 10: DNA Replication - Medical Animation
 
This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this animation for other purposes, click here.

If animation does not play, download and install the latest free Flash Player plugin.
More Like ThisAdd To Lightbox NSV16037 Enlarge Share
Ready to Purchase?

$999.00

Order by phone: (800) 338-5954
Item #NSV16037Source #1

Biology: Genetics: 10: DNA Replication - Medical Animation
MEDICAL ANIMATION TRANSCRIPT:
Let's take a look at DNA replication, the process in which DNA copies itself. Why does DNA need to copy itself? Well, before a cell divides during mitosis, it must make a copy of its original DNA. This ensures that both resulting daughter cells will have DNA that is identical to the original cell's DNA. So at what point in the cell cycle does DNA replication happen? DNA is copied or replicated during the S phase of the cell cycle. A good way to remember this is that S stands for synthesis, which means to make. Now, let's see how DNA replicates during the S phase. If we zoom into the nucleus, we can see the DNA molecules two strands or sides twisted together in the classic double-helix formation. The two strands are connected by hydrogen bonds between their nitrogenous bases. The first step of replication begins with an enzyme called DNA helicase. The suffix A-S-E or ASE tells you right away that helicase is an enzyme. Helicase unwinds and then separates the two sides of the DNA molecule by breaking the hydrogen bonds between their nitrogenous bases. Each separate half of the DNA can now serve as a template or pattern for the creation of a new strand of DNA. This separation exposes all of the nitrogenous bases on both sides of the DNA to the environment within the nucleus where free nucleotides are present. This brings us to the second step in DNA replication, the creation of two new identical DNA strands. An enzyme that assists in this process is called DNA polymerase. It adds free nucleotides available in the nucleus to the original template strands. DNA polymerase does this by creating new hydrogen bonds between the available nitrogenous bases of the free nucleotides and those on both sides of the original DNA molecule. New nucleotides are added to the template strands following the base pair rule of nitrogenous bases. Remember, in DNA, adenine always bonds with thymine. Thymine always bonds with adenine. Guanine always bonds with cytosine, and cytosine always bonds with guanine. So these newly attached nucleotides form a mirror image or complementary strand on each template strand of the original DNA. As a result of this replication process, two duplicate molecules of DNA are produced from the original DNA molecule. With DNA replication now completed, the cell is ready to begin mitosis. We will cover mitosis in another video. In summary, DNA replication is a process in which DNA duplicates itself, making an identical copy. Replication occurs during the S phase of the cell cycle when a somatic cell is preparing to divide. DNA replication is necessary so that the two daughter cells produced after mitosis both have DNA that is identical to each other and identical to the DNA in the original cell. At the beginning of replication, an enzyme called DNA helicase breaks the hydrogen bonds between nitrogenous bases and unwinds the DNA molecule. Each side of the original DNA molecule serves as a template for the creation of a new complementary strand of DNA. With the assistance of DNA polymerase and other enzymes, free nucleotides are added to the template strands following the base pair rule. The result of DNA replication is two identical duplicate DNA molecules from the original DNA molecule. ♪ [music] ♪

YOU MAY ALSO WANT TO REVIEW THESE ITEMS:
Chemical Inhalation Resulting in Lung Damage
Chemical Inhalation Resulting in Lung Damage - exh4677a
Medical Exhibit
Add to my lightbox
Find More Like This
Mitral Valve Prolapse
Mitral Valve Prolapse - exh37285a
Medical Exhibit
Add to my lightbox
Find More Like This
Drainage of Pelvic Abscess
Drainage of Pelvic Abscess - exh46691e
Medical Exhibit
Add to my lightbox
Find More Like This
Helicase Enzyme
Helicase Enzyme - ANS00056
Medical Animation
Add to my lightbox
Find More Like This
Bile Leak
Bile Leak - AL00229
Medical Illustration
Add to my lightbox
Find More Like This
Thoracic Spinal Hematoma
Thoracic Spinal Hematoma - exh70298
Medical Exhibit
Add to my lightbox
Find More Like This
What attorneys say about MLA and The Doe Report:
"We are extremely pleased with the quality of the medical exhibits and the timely manner in which they were provided. I will certainly recommend your company to my business associates who could benefit from your services. Please tell Brian Wilson [Director of Content Development, Senior Medical Illustrator] that he did an exceptional job on these exhibits."

K. Henderson
Dunaway and Associates
Anderson, SC

"Our practice involves medical negligence cases exclusively. We have six attorneys and one physician on staff. We have used Medical Legal Art's staff for every one of our cases over the past 12 years and have found their services to be extraordinary. The transformation of medical records into powerful graphic images has without fail been handled expertly, expeditiously and effectively translating into superb results for our clients, both in the courtroom and in settlement. Every case can benefit from their excellent work and we unqualifiedly recommend their services. They are the best!"

Chris Otorowski
Morrow and Otorowski
Bainbridge Island, Washington
www.medilaw.com

"I wanted to take some time out to let you know what a wonderful job you did with the 'collapsed lung/fractured rib' illustrations. They were both detailed and accurate. My medical expert was comfortable working with them and he spent at least an hour explaining to the jury the anatomy of the lungs, the ribs and the injuries depicted in the illustrations. Needless to say, the jury was riveted to the doctor during his testimony.

The jury returned a verdict for $800,000.00 and I'm sure we would not have done so well if not for the visualizations we were able to put forth with your assistance. Lastly, my special thanks to Alice [Senior Medical Illustrator] who stayed late on Friday night and patiently dealt with my last minute revisions."

Daniel J. Costello
Proner & Proner
New York, NY

"For us, the defining feature of effective demonstrative evidence is whether, by itself, the piece will tell the story of the case. Medical legal Art provides our firm with illustrations and animations that are clear and persuasive. Their exhibits tell the story in a way that allows the jury to understand a very complex subject, very quickly."

James D. Horwitz
Koskoff, Koskoff & Bieder, P.C.
Bridgeport, CT













Awards | Resources | Articles | Become an Affiliate | Free Medical Images | Pregnancy Videos
Credits | Jobs | Help | Medical Legal Blog | Find a Lawyer | Hospital Marketing