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Alzheimer's Disease - Medical Animation
 
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Alzheimer's Disease - Medical Animation
MEDICAL ANIMATION TRANSCRIPT:

The brain's cognitive functions include memory, which is the process of information retention and retrieval. Memories form in the hippocampus, which consists of information-processing cells called neurons. Each neuron receives chemical messages from other neurons via dendrites, then converts the message to an electrical charge called an action potential. In the space between them, neurons release stimulatory chemicals called neurotransmitters, which bind with receptors on the receiving cell and transfer information. Alzheimer's disease is a gradual, degenerative brain condition in which neurons in the memory and other cognitive areas of the brain lose function and die, resulting in progressive memory loss first, then difficulties learning and communicating, and, eventually, failing basic functions like breathing. In healthy neurons, enzymes help process a protein called amyloid precursor protein into fragments which help with normal cell function. In Alzheimer's, abnormal enzymatic processing produces fragments that include a sticky peptide called beta amyloid. Beta amyloid accumulates in the extracellular space, forming clumps called amyloid plaques. These clumps block the electrical and chemical connections between neurons. Inside healthy neurons, microtubules and tau proteins form an orderly structure that carries ions and nutrients within the cell. In Alzheimer's, chemical changes inside the neurons damage tau, twisting microtubules abnormally into neurofibrillary tangles, which disrupts ion and nutrient delivery within the cell. As the plaques and tangles multiply throughout brain tissue, neural connections diminish, and the malnourished cells lose function, resulting in widespread neural death, reduced brain mass, and severe cognitive and functional impairment. There is no cure for Alzheimer's, but current treatments include cholinesterase inhibitors, which delay the breakdown of acetylcholine, a neurotransmitter important for memory and learning, and antiglutamatergic medications, which regulate the activity of glutamate, another neurotransmitter essential for memory and learning, by blocking excessive glutamate binding to neurons, thus preventing neuronal dysfunction and death. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"The illustrations have consistently been well documented, accurate and timely. Most important though is that the illustrations demonstrate to juries and claims people the persuasive power of visual communication. Our firm has achieved multiple eight figure settlements and verdicts over the past ten years... Medical Legal Art has been there with us on every case."

Thomas C. Jones
Davis, Bethune & Jones, L.L.C.
Kansas City, MO
www.dbjlaw.net

"I have found that the personalized medical illustrations prepared by Medical Legal Art have been very accurate and helpful. The medical doctors, both treating physicians and expert witnesses, have commented on the accuracy and professionalism of the medical illustrations. Most importantly, your prompt service and attention upon even short notice has been tremendous. I can certainly say that the medical illustrations prepared by Medical Legal Art have assisted us in bringing cases to a successful resolution."

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The Redfearn Law Firm, P.C.
Kansas City, MO

"Our practice involves medical negligence cases exclusively. We have six attorneys and one physician on staff. We have used Medical Legal Art's staff for every one of our cases over the past 12 years and have found their services to be extraordinary. The transformation of medical records into powerful graphic images has without fail been handled expertly, expeditiously and effectively translating into superb results for our clients, both in the courtroom and in settlement. Every case can benefit from their excellent work and we unqualifiedly recommend their services. They are the best!"

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Morrow and Otorowski
Bainbridge Island, Washington
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Viles Law Firm, P.A.
Fort Meyers, FL













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