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Alzheimer's Disease - Medical Animation

 

This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this image for other purposes, click here.

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Alzheimer's Disease - Medical Animation
MEDICAL ANIMATION TRANSCRIPT: The brain's cognitive functions include memory, which is the process of information retention and retrieval. Memories form in the hippocampus, which consists of information-processing cells called neurons. Each neuron receives chemical messages from other neurons via dendrites, then converts the message to an electrical charge called an action potential. In the space between them, neurons release stimulatory chemicals called neurotransmitters, which bind with receptors on the receiving cell and transfer information. Alzheimer's disease is a gradual, degenerative brain condition in which neurons in the memory and other cognitive areas of the brain lose function and die, resulting in progressive memory loss first, then difficulties learning and communicating, and, eventually, failing basic functions like breathing. In healthy neurons, enzymes help process a protein called amyloid precursor protein into fragments which help with normal cell function. In Alzheimer's, abnormal enzymatic processing produces fragments that include a sticky peptide called beta amyloid. Beta amyloid accumulates in the extracellular space, forming clumps called amyloid plaques. These clumps block the electrical and chemical connections between neurons. Inside healthy neurons, microtubules and tau proteins form an orderly structure that carries ions and nutrients within the cell. In Alzheimer's, chemical changes inside the neurons damage tau, twisting microtubules abnormally into neurofibrillary tangles, which disrupts ion and nutrient delivery within the cell. As the plaques and tangles multiply throughout brain tissue, neural connections diminish, and the malnourished cells lose function, resulting in widespread neural death, reduced brain mass, and severe cognitive and functional impairment. There is no cure for Alzheimer's, but current treatments include cholinesterase inhibitors, which delay the breakdown of acetylcholine, a neurotransmitter important for memory and learning, and antiglutamatergic medications, which regulate the activity of glutamate, another neurotransmitter essential for memory and learning, by blocking excessive glutamate binding to neurons, thus preventing neuronal dysfunction and death. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"Thank you for the splendid medical-legal art work you did for us in the case of a young girl who was blinded by a bb pellet. As a result of your graphic illustrations of this tragic injury, we were able to persuade the insurance company to increase their initial offer of $75,000.00 to $475,000.00, just short of their policy limits.

We simply wanted you to know how pleased we were with your work which, to repeat, was of superlative character, and to let you know that we would be more than willing to serve as a reference in case you ever need one. Many thanks for an extraordinary and dramatic depiction of a very serious injury which clearly "catapulted" the insurance company's offer to a "full and fair" amount to settle this case."

Philip C. Coulter
Coulter &Coulter
Roanoke, VA

"This past year, your company prepared three medical illustrations for our cases; two in which we received six figure awards; one in which we received a substantial seven figure award. I believe in large part, the amounts obtained were due to the vivid illustrations of my clients' injuries and the impact on the finder of fact."

Donald W. Marcari
Marcari Russotto & Spencer, P.C.
Chesapeake, VA
"It is my experience that it's much more effective to show a jury what happened than simply to tell a jury what happened. In this day and age where people are used to getting information visually, through television and other visual media, I would be at a disadvantage using only words.

I teach a Litigation Process class at the University of Baltimore Law Schooland use [Medical Legal Art's] animation in my class. Students always saythat they never really understood what happened to [to my client] until theysaw the animation.

Animations are powerful communication tools that should be used wheneverpossible to persuade juries."

Andrew G. Slutkin
Snyder Slutkin & Kopec
Baltimore, MD
"I thought you might want to know that after we sent a copy of your illustration to the defendants, with a copy to the insurance company, they increased their offer by an additional million dollars and the case was settled for $1,900,000.00.

I appreciate your help!"

O. Fayrell Furr, Jr.
Furr, Henshaw & Ohanesian
Myrtle Beach, SC
www.scmedicalmalpractice.com













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