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Hyperthyroidism - Medical Animation

 

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Hyperthyroidism - Medical Animation
MEDICAL ANIMATION TRANSCRIPT: The thyroid is the body's largest endocrine gland and is located anterior and lateral to the trachea and inferior to the larynx. One of the functions of the thyroid is to secrete thyroid hormone, which increases metabolic rate by increasing respiratory rate, increasing heart rate, accelerating breakdown of food for fuel, and increasing heat production. The thyroid hormone interacts with the hypothalamus and pituitary gland in a negative feedback loop to affect metabolic rate. Low levels of thyroid hormone in the blood cause the hypothalamus to release thyrotropin-releasing hormone. Thyrotropin-releasing hormone stimulates the anterior pituitary to release thyroid-stimulating hormone. Thyroid-stimulating hormone stimulates the thyroid gland to secrete thyroid hormones triiodothyronine, or T3, and thyroxine, or T4, into the bloodstream to affect cells throughout the body. The elevated levels of thyroxine in the blood are detected by the hypothalamus which stops production of thyrotropin-releasing hormone. This negative feedback loop keeps the metabolic rate from increasing too much. Hyperthyroidism is a condition in which there is a chronic high level of thyroid hormone present in the blood. The most common cause is Grave's disease, an idiopathic autoimmune disorder. In this condition, B cells in the thyroid mistakenly produce thyroid-stimulating immunoglobulins, which mimic the effect of thyroid-stimulating hormone and bind to the same receptor. As a result, binding these immunoglobulins stimulates the thyroid gland to continue producing thyroid hormone, which causes chronic manifestations of increased respiration, increased heart rate, called tachycardia, and increased heat production. In addition, the thyroid gland increases in size, resulting in a condition called thyroid hypertrophy or a goiter. Three common treatments of hyperthyroidism reduce circulating thyroid hormone. Antithyroid drugs such as propylthiouracil and methimazole suppress the synthesis of thyroid hormone. Surgical removal of thyroid tissue can reduce the amount of secreted thyroid hormone. Oral ingestion of radioactive iodine destroys thyroid tissue, resulting in decreased secretion of thyroid hormone. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"This past year, your company prepared three medical illustrations for our cases; two in which we received six figure awards; one in which we received a substantial seven figure award. I believe in large part, the amounts obtained were due to the vivid illustrations of my clients' injuries and the impact on the finder of fact."

Donald W. Marcari
Marcari Russotto & Spencer, P.C.
Chesapeake, VA

"Our firm was able to settle our case at an all day mediation yesterday and I am confident that the detail and overall appearance of the medical illustrations significantly contributed to the settlement. When we require medical illustrations in the future, I will be sure to contact [MLA]."

Noel Turner, III
Burts, Turner, Rhodes & Thompson
Spartanburg, SC

"At 3 PM it hit me--I needed exhibits of a tracheostomy, a coronary artery bypass and a deep vein thrombosis--all in time for a for-trial video deposition the next day. The Doe Report had each exhibit on line. In addition, I ran across an exhibit I hadn't even thought of: reduced ejection fraction after a heart attack. Because this was a video deposition, I could use the e-mail version of the medical exhibit, print it on my color copier, and let the camera zoom in. For $400, less than one blow-up by one of The Doe Report's competitors, I got four first-rate exhibits in less than a day. The Doe Report saved me time and money."

Tracy Kenyon Lischer
Pulley Watson King & Lischer
Durham, NC
www.PWKL.com

"I wanted to take some time out to let you know what a wonderful job you did with the 'collapsed lung/fractured rib' illustrations. They were both detailed and accurate. My medical expert was comfortable working with them and he spent at least an hour explaining to the jury the anatomy of the lungs, the ribs and the injuries depicted in the illustrations. Needless to say, the jury was riveted to the doctor during his testimony.

The jury returned a verdict for $800,000.00 and I'm sure we would not have done so well if not for the visualizations we were able to put forth with your assistance. Lastly, my special thanks to Alice [Senior Medical Illustrator] who stayed late on Friday night and patiently dealt with my last minute revisions."

Daniel J. Costello
Proner & Proner
New York, NY













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