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Hyperthyroidism - Medical Animation
 
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Hyperthyroidism - Medical Animation
MEDICAL ANIMATION TRANSCRIPT:
The thyroid is the body's largest endocrine gland and is located anterior and lateral to the trachea and inferior to the larynx. One of the functions of the thyroid is to secrete thyroid hormone, which increases metabolic rate by increasing respiratory rate, increasing heart rate, accelerating breakdown of food for fuel, and increasing heat production. The thyroid hormone interacts with the hypothalamus and pituitary gland in a negative feedback loop to affect metabolic rate. Low levels of thyroid hormone in the blood cause the hypothalamus to release thyrotropin-releasing hormone. Thyrotropin-releasing hormone stimulates the anterior pituitary to release thyroid-stimulating hormone. Thyroid-stimulating hormone stimulates the thyroid gland to secrete thyroid hormones triiodothyronine, or T3, and thyroxine, or T4, into the bloodstream to affect cells throughout the body. The elevated levels of thyroxine in the blood are detected by the hypothalamus which stops production of thyrotropin-releasing hormone. This negative feedback loop keeps the metabolic rate from increasing too much. Hyperthyroidism is a condition in which there is a chronic high level of thyroid hormone present in the blood. The most common cause is Grave's disease, an idiopathic autoimmune disorder. In this condition, B cells in the thyroid mistakenly produce thyroid-stimulating immunoglobulins, which mimic the effect of thyroid-stimulating hormone and bind to the same receptor. As a result, binding these immunoglobulins stimulates the thyroid gland to continue producing thyroid hormone, which causes chronic manifestations of increased respiration, increased heart rate, called tachycardia, and increased heat production. In addition, the thyroid gland increases in size, resulting in a condition called thyroid hypertrophy or a goiter. Three common treatments of hyperthyroidism reduce circulating thyroid hormone. Antithyroid drugs such as propylthiouracil and methimazole suppress the synthesis of thyroid hormone. Surgical removal of thyroid tissue can reduce the amount of secreted thyroid hormone. Oral ingestion of radioactive iodine destroys thyroid tissue, resulting in decreased secretion of thyroid hormone. ♪ [music] ♪

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"I have found that the personalized medical illustrations prepared by Medical Legal Art have been very accurate and helpful. The medical doctors, both treating physicians and expert witnesses, have commented on the accuracy and professionalism of the medical illustrations. Most importantly, your prompt service and attention upon even short notice has been tremendous. I can certainly say that the medical illustrations prepared by Medical Legal Art have assisted us in bringing cases to a successful resolution."

Paul L. Redfearn
The Redfearn Law Firm, P.C.
Kansas City, MO

"The Doe Report's Do-It-Yourself Exhibits program enables easy customization of complex medical exhibits at a reasonable expense and in a timely manner. Practically speaking, custom medical exhibits are no longer an unthinkable luxury, but a routine necessity."

Jack S. Cohen
Levy, Angstreich, Finney, Baldante & Coren
Philadelphia, PA

"Medical illustrations are essential evidence in personal injury litigation and MLA is simply the best I've found at producing high-quality illustrations. Your illustrators are not only first-class artists, but creative and responsive. Your turn around time is as good as it gets. My clients have won over $60 million in jury verdicts and I can't recall a case which did not include one of your exhibits. On behalf of those clients, thanks and keep up the great work!"

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Valparaiso, IN
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