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Inflammation - Medical Animation

 

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Inflammation - Medical Animation
MEDICAL ANIMATION TRANSCRIPT: Inflammation is a local immune response to tissue injury or infection, experienced as heat, redness, edema, pain, and loss of function. Immediately after injury, inflammation begins with brief vasoconstriction of the local blood vessels to reduce blood loss and formation of a clot to stop the bleeding. Then, stimulated by cell injury and death, local cells release vasoactive chemicals, such as prostaglandins and histamine to dilate local blood vessels leading to increased blood flow to the area. These chemicals also cause endothelial cells in small blood vessels to contract, opening spaces between them. This increased capillary permeability allows fluids and proteins to pass from the blood into the tissue. Next, during a multi-stage process called chemotaxis, circulating immune cells called neutrophils move out of the blood vessels to the site of injury and destroy pathogens and damaged cells. Chemotaxis begins when cells at the injury site release messenger molecules called chemoattractants, which cause local endothelial cells and circulating neutrophils to stick together. Next, in a process called diapedesis, neutrophils squeeze through the endothelial gaps. The neutrophils migrate to the injury site by following a chemotactic gradient. Upon arrival, the neutrophils encounter bacteria, engulf them and digest them in a process called phagocytosis. After destruction of the bacteria and removal of cellular waste, tissue repair begins when locally produced growth factors cause local fibroblasts to begin dividing rapidly and secreting large quantities of collagen to reinforce the wound. Anti-inflammatory drugs inhibit inflammation by blocking production of inflammatory chemicals. The most common drugs for inflammation are non-steroidal anti-inflammatory drugs, or NSAIDS, such as aspirin and ibuprofen. They contain an enzyme called cyclooxygenase or COX, that inhibits the production of prostaglandins and several other inflammatory chemicals. Thus, reducing vasodilation, edema, and pain associated with inflammation. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"For us, the defining feature of effective demonstrative evidence is whether, by itself, the piece will tell the story of the case. Medical legal Art provides our firm with illustrations and animations that are clear and persuasive. Their exhibits tell the story in a way that allows the jury to understand a very complex subject, very quickly."

James D. Horwitz
Koskoff, Koskoff & Bieder, P.C.
Bridgeport, CT

"I just wanted to let you know that after several days on trial, I settled [my client's] construction accident case for $4.5 million. Immediately after the jury was discharged, I spoke with several jurors who told me that they really appreciated the medical illustrations for their clarity in dealing with [my client's] devastating injuries. They also expressed their gratitude in being able to read from a distance all of the notations without difficulty. Obviously, the boards were visually persuasive. I am certain that this contributed to our successful result."

Michael Gunzburg, Esq.
Attorney at Law.
New York, NY

"Your firm is great to work with and, most importantly for me, you get the job done on time and with the utmost professionalism. You should be proud of all those you employ, from KJ to Ben B. I've been especially pleased over the years with the work of Brian and Alice, both of whom seem to tolerate my idiosycratic compulsion to edit, but I've not found a bad apple in the bunch (and, as you know, I've used your firm a bunch!). I look forward to our continued professional relationship."

Kenneth J. Allen
Kenneth Allen & Associates
Valparaiso, IN

"This past year, your company prepared three medical illustrations for our cases; two in which we received six figure awards; one in which we received a substantial seven figure award. I believe in large part, the amounts obtained were due to the vivid illustrations of my clients' injuries and the impact on the finder of fact."

Donald W. Marcari
Marcari Russotto & Spencer, P.C.
Chesapeake, VA













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