Follow us On YouTube Follow us On FaceBook



or
Search Language
Browse
Medical Animations
Medical Animation Titles
Custom Legal Animations
Patient Health Articles
Most Recent Uploads
Body Systems/Regions
Anatomy & Physiology
Diseases & Conditions
Diagnostics & Surgery
Cells & Tissues
Cardiovascular System
Digestive System
Integumentary System
Nervous System
Reproductive System
Respiratory System
Back and Spine
Foot and Ankle
Head and Neck
Hip
Knee
Shoulder
Thorax
Medical Specialties
Cancer
Cardiology
Dentistry
Editorial
Neurology/Neurosurgery
Ob/Gyn
Orthopedics
Pediatrics
Account
Administrator Login

Medication Excretion - Medical Animation

 

This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this image for other purposes, click here.

Ready to License?

Item #ANM10007 — Source #1

Order by phone: (800) 338-5954

Medication Excretion - Medical Animation
MEDICAL ANIMATION TRANSCRIPT: The body filters drugs from the bloodstream and eliminates them in a multi-step process called medication excretion. The kidneys are the major route for drug elimination. Most drugs exit the body either unchanged or as drug metabolites in urine. Generally, health professionals refer to the ability of the kidneys to filter blood as renal function. Nephrons, the functional and anatomical units of the kidney, filter blood, regulate fluid volume and pH, and control levels of electrolytes in the body. Each nephron contains a renal corpuscle and renal tubule. The renal corpuscle includes the Bowman capsule and glomerulus. And the renal tubule is composed of the proximal tubule, loop of Henle, distal tubule, and collecting duct. Each component plays a role in renal drug excretion, a four-step process that allows the kidneys to filter and eliminate drugs from the body. These steps are: glomerular filtration, passive tubular reabsorption, active tubular secretion, and excretion. Blood flows into the glomerulus via a blood vessel larger in diameter than the vessel draining blood from the glomerulus. This difference in diameter creates the high blood pressure necessary to filter wastes from the blood. The glomerulus functions as a molecular sieve. Waste materials in water pass through the sieve, while most normal proteins and cells are kept in the bloodstream. Glomerular filtration removes low-molecular-weight drugs from the bloodstream. The process of passive reabsorption of water, solutes, and ions begins in the proximal tubule, continues in the Henle loop, and ends in the distal and collecting ducts. Water-soluble drugs stay in the tubule, while unionized and lipid-soluble drugs are primarily reabsorbed across renal tubules. After reabsorption, lipid-soluble drugs travel through the bloodstream to the liver where certain liver enzymes, such as the cytochrome P450 enzyme complex, metabolize them into more water-soluble forms. Here we show an example of this process through the metabolism of pentobarbital. Some drugs are not filtered from the blood via the glomerulus. Instead, special anionic and cationic pumps in the walls of the renal tubule actively transport the drugs from the blood into the tubules and collecting duct. Urine from the collecting ducts travel through the ureters where it is collected and stored in the urinary bladder until elimination from the body. Although the kidneys are the major route for drug elimination, medication excretion can also occur in lactating women through their breast milk, exhalation through the lungs, release into bile, and elimination through saliva and sweat. [music]

YOU MAY ALSO WANT TO REVIEW THESE ITEMS:
Anatomy of a Neuron (Nerve Cell)
Anatomy of a Neuron (Nerve Cell) - ANS00035
Medical Animation
Add to my lightbox
Find More Like This
Anatomy and Physiology of the Kidney
Anatomy and Physiology of the Kidney - exh4866a
Medical Exhibit
Add to my lightbox
Find More Like This
Anatomy and Physiology of the Kidney
Anatomy and Physiology of the Kidney - exh4866a-nl
Medical Exhibit
Add to my lightbox
Find More Like This
Anatomy of the Abdominal Blood Vessels
Anatomy of the Abdominal Blood Vessels - exh39956a
Medical Exhibit
Add to my lightbox
Find More Like This
Anatomy and Physiology of the Brain
Anatomy and Physiology of the Brain - ANS12530
Medical Animation
Add to my lightbox
Find More Like This
Anatomy of the Kidneys and Renal Blood Vessels
Anatomy of the Kidneys and Renal Blood Vessels - exh43374b
Medical Exhibit
Add to my lightbox
Find More Like This
What attorneys say about MLA and The Doe Report:
"The Doe Report is a visual feast of medical information for personal injury lawyers."

Aaron R. Larson, Esq.
President
ExpertLaw.com

"We are extremely pleased with the quality of the medical exhibits and the timely manner in which they were provided. I will certainly recommend your company to my business associates who could benefit from your services. Please tell Brian Wilson [Director of Content Development, Senior Medical Illustrator] that he did an exceptional job on these exhibits."

K. Henderson
Dunaway and Associates
Anderson, SC

"Thanks, and your illustrations were effective in a $3 million dollar verdict last Friday."

Joseph M. Prodor
Trial Lawyer
White Rock, British Columbia
"This past year, your company prepared three medical illustrations for our cases; two in which we received six figure awards; one in which we received a substantial seven figure award. I believe in large part, the amounts obtained were due to the vivid illustrations of my clients' injuries and the impact on the finder of fact."

Donald W. Marcari
Marcari Russotto & Spencer, P.C.
Chesapeake, VA













Awards | Resources | Articles | Become an Affiliate | Free Medical Images | Pregnancy Videos
Credits | Jobs | Help | Medical Legal Blog | Find a Lawyer | Hospital Marketing