Quantcast
Follow us On YouTube Follow us On FaceBook



or
Search Language
Browse
Medical Animations
Medical Animation Titles
Custom Legal Animations
Patient Health Articles
Custom Interactive
Most Recent Uploads
Body Systems/Regions
Anatomy & Physiology
Diseases & Conditions
Diagnostics & Surgery
Cells & Tissues
Cardiovascular System
Digestive System
Integumentary System
Nervous System
Reproductive System
Respiratory System
Back and Spine
Foot and Ankle
Head and Neck
Hip
Knee
Shoulder
Thorax
Medical Specialties
Cancer
Cardiology
Dentistry
Editorial
Neurology/Neurosurgery
Ob/Gyn
Orthopedics
Pediatrics
Account
Administrator Login
Medication Excretion - Medical Animation
 
This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this animation for other purposes, click here.

If animation does not play, download and install the latest free Flash Player plugin.
More Like ThisAdd To Lightbox ANM10007 Enlarge Share
Ready to Purchase?

$999.00

Order by phone: (800) 338-5954
Item #ANM10007Source #1

Medication Excretion - Medical Animation
MEDICAL ANIMATION TRANSCRIPT:
The body filters drugs from the bloodstream and eliminates them in a multi-step process called medication excretion. The kidneys are the major route for drug elimination. Most drugs exit the body either unchanged or as drug metabolites in urine. Generally, health professionals refer to the ability of the kidneys to filter blood as renal function. Nephrons, the functional and anatomical units of the kidney, filter blood, regulate fluid volume and pH, and control levels of electrolytes in the body. Each nephron contains a renal corpuscle and renal tubule. The renal corpuscle includes the Bowman capsule and glomerulus. And the renal tubule is composed of the proximal tubule, loop of Henle, distal tubule, and collecting duct. Each component plays a role in renal drug excretion, a four-step process that allows the kidneys to filter and eliminate drugs from the body. These steps are: glomerular filtration, passive tubular reabsorption, active tubular secretion, and excretion. Blood flows into the glomerulus via a blood vessel larger in diameter than the vessel draining blood from the glomerulus. This difference in diameter creates the high blood pressure necessary to filter wastes from the blood. The glomerulus functions as a molecular sieve. Waste materials in water pass through the sieve, while most normal proteins and cells are kept in the bloodstream. Glomerular filtration removes low-molecular-weight drugs from the bloodstream. The process of passive reabsorption of water, solutes, and ions begins in the proximal tubule, continues in the Henle loop, and ends in the distal and collecting ducts. Water-soluble drugs stay in the tubule, while unionized and lipid-soluble drugs are primarily reabsorbed across renal tubules. After reabsorption, lipid-soluble drugs travel through the bloodstream to the liver where certain liver enzymes, such as the cytochrome P450 enzyme complex, metabolize them into more water-soluble forms. Here we show an example of this process through the metabolism of pentobarbital. Some drugs are not filtered from the blood via the glomerulus. Instead, special anionic and cationic pumps in the walls of the renal tubule actively transport the drugs from the blood into the tubules and collecting duct. Urine from the collecting ducts travel through the ureters where it is collected and stored in the urinary bladder until elimination from the body. Although the kidneys are the major route for drug elimination, medication excretion can also occur in lactating women through their breast milk, exhalation through the lungs, release into bile, and elimination through saliva and sweat. ♪ [music] ♪

YOU MAY ALSO WANT TO REVIEW THESE ITEMS:
Post-operative Gangrene of the Left Foot with Amputation
Post-operative Gangrene of the Left Foot with Amputation - exh4781d
Medical Exhibit
Add to my lightbox
Find More Like This
Left Shoulder Injuries
Left Shoulder Injuries - exh37502
Medical Exhibit
Add to my lightbox
Find More Like This
Plantar Fasciitis: Treatment Exercise
Plantar Fasciitis: Treatment Exercise - si55551789
Medical Illustration
Add to my lightbox
Find More Like This
Medication Absorption
Medication Absorption - ANM11011
Medical Animation
Add to my lightbox
Find More Like This
Medication Metabolism
Medication Metabolism - ANM11010
Medical Animation
Add to my lightbox
Find More Like This
Pharmacodynamics - Pharmacokinectics
Pharmacodynamics - Pharmacokinectics - ANM11012
Medical Animation
Add to my lightbox
Find More Like This
What attorneys say about MLA and The Doe Report:
"I just wanted to let you know that after several days on trial, I settled [my client's] construction accident case for $4.5 million. Immediately after the jury was discharged, I spoke with several jurors who told me that they really appreciated the medical illustrations for their clarity in dealing with [my client's] devastating injuries. They also expressed their gratitude in being able to read from a distance all of the notations without difficulty. Obviously, the boards were visually persuasive. I am certain that this contributed to our successful result."

Michael Gunzburg, Esq.
Attorney at Law.
New York, NY

"At 3 PM it hit me--I needed exhibits of a tracheostomy, a coronary artery bypass and a deep vein thrombosis--all in time for a for-trial video deposition the next day. The Doe Report had each exhibit on line. In addition, I ran across an exhibit I hadn't even thought of: reduced ejection fraction after a heart attack. Because this was a video deposition, I could use the e-mail version of the medical exhibit, print it on my color copier, and let the camera zoom in. For $400, less than one blow-up by one of The Doe Report's competitors, I got four first-rate exhibits in less than a day. The Doe Report saved me time and money."

Tracy Kenyon Lischer
Pulley Watson King & Lischer
Durham, NC
www.PWKL.com

"A few words about The Doe Report: recently in a brachial plexus injury case, we used an image from The Doe Report to demonstrate the injury. We downloaded the PDF file image, and were amazed at the quality. The hard copies that you sent were even more clear. As well, we could not have been happier when you customized the image and reversed the injury from the left shoulder to the right shoulder, which is where our client's injury was.

The speed and cost-effectiveness of the product made it the perfect tool for our purposes. We will use The Doe Report again in future cases."

Andrew Needle
Needle Gallagher & Ellenberg, P.A.
Miami, FL

"[Your staff] was extremely efficient, cooperative and gracious and [their] efforts produced a demonstrative exhibit that we used effectively throughout our trial. The jury verdict of $3,165,000.00 was, in no small measure, due to the impact of the demonstrative evidence. You may be sure that we will call again."

David J. Dean
Sullivan Papain Block McGrath & Cannavo, P.C.
New York, NY













Awards | Resources | Articles | Become an Affiliate | Free Medical Images | Pregnancy Videos
Credits | Jobs | Help | Medical Legal Blog | Find a Lawyer | Hospital Marketing