Follow us On YouTube Follow us On FaceBook



or
Search Language
Browse
Medical Animations
Medical Animation Titles
Custom Legal Animations
Patient Health Articles
Most Recent Uploads
Body Systems/Regions
Anatomy & Physiology
Diseases & Conditions
Diagnostics & Surgery
Cells & Tissues
Cardiovascular System
Digestive System
Integumentary System
Nervous System
Reproductive System
Respiratory System
Back and Spine
Foot and Ankle
Head and Neck
Hip
Knee
Shoulder
Thorax
Medical Specialties
Cancer
Cardiology
Dentistry
Editorial
Neurology/Neurosurgery
Ob/Gyn
Orthopedics
Pediatrics
Account
Administrator Login
Biology: The Cell: 10: Cell Division - Mitosis and Cytokinesis - Medical Animation
 
This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this animation for other purposes, click here.

If animation does not play, download and install the latest free Flash Player plugin.
More Like ThisAdd To Lightbox NSV15006 Enlarge
Ready to Purchase?

$999.00

Order by phone: (800) 338-5954
Item #NSV15006Source #1

Biology: The Cell: 10: Cell Division - Mitosis and Cytokinesis - Medical Animation
MEDICAL ANIMATION TRANSCRIPT: In this lesson, we'll be exploring the M phase of the cell cycle including mitosis and cytokinesis. Let's do a quick review of the cell cycle to see where they fit in. The G1, S, and G2 phases make up interphase, and the M phase represents cell division. Cell division includes division of the nucleus, called mitosis, and division of the cytoplasm, called cytokinesis. Mitosis is further broken down into four phases: prophase, metaphase, anaphase, and telophase. Prophase is the longest phase of mitosis. Prophase is when chromatin begins to condense into the shape of chromosomes, and the nucleolus disappears. The previously replicated DNA coils tightly into sister chromatids. For the first time, you see individual chromosomes. In the center of each chromosome, a centromere attaches the sister chromatids together. Meanwhile, in the cytoplasm, microtubules known as spindle fibers begin to fan out from two sets of paired structures called centrioles. The spindle fibers elongate as the centrioles begin moving to opposite sides, or poles, of the cell. While this is happening, the nuclear membrane surrounding the nucleus disappears. Now that chromosomes are no longer separated from the cytoplasm, the opposite ends of the spindle fibers can attach to the centromeres. Next, the cell enters metaphase. The centrioles complete their movement to the poles of the cell while the spindle fibers line up the chromosomes along the equator of the cell. The end-to-end alignment of chromosomes results in a sister chromatid on either side of the equator. Anaphase follows metaphase. During anaphase, spindle fibers separate the sister chromatids at their centromere. Once separated from each other, each chromatid is called a chromosome. The single-stranded chromosomes form a V shape as the spindle fibers shorten and drag them through the gel-like cytoplasm. The chromosomes move to opposite poles of the cell toward their centrioles. It's common to confuse centrioles with centromeres which connect chromatids. Remember, centrioles are at the poles. Telophase is the final stage of mitosis. In telophase, a nuclear membrane re-forms around each set of chromosomes. Then the chromosomes spread out into chromatin, and the nucleolus becomes visible once again. Mitosis, the division of the nucleus, is now complete. The final step of the M phase is cytokinesis, the division of the cytoplasm. In animal cells, cytokinesis occurs through the inward movement of the cell membrane. This progressively pinches the cytoplasm until two identical daughter cells form. In contrast, plant cells can't pinch in two because they have a rigid cell wall surrounding their cell membrane. Instead, cell wall material assembles along the equator forming a structure called the cell plate. The cell plate grows until it joins with the existing cell membrane, separating the two halves of the cell into daughter cells. Over time, new cell walls form between the two daughter cells. Here are the key points to remember. The M phase is the fourth and final phase of the cell cycle. During the M phase, cell division occurs through two processes: mitosis, when the nucleus divides, and cytokinesis, when the cytoplasm divides. Mitosis has four phases. During prophase, chromatin condenses into chromosomes, spindle fibers form, and the nucleolus and nuclear membrane disappear. During metaphase, spindle fibers align the chromosomes along the cell equator. In anaphase, the spindle fibers separate sister chromatids into two separate groups of chromosomes, pulling them toward the poles. And in telophase, the nucleolus and nuclear membrane re-form. The chromosomes disperse into chromatin. Cytokinesis is division of the cytoplasm. The M phase is complete after cytokinesis occurs. The M phase of the cell cycle always results in two daughter cells. Both of these daughter cells are identical to each other and identical to the original cell that underwent mitosis. [music]

YOU MAY ALSO WANT TO REVIEW THESE ITEMS:
Brain Injury to the Cerebrum and Cerebellum
Brain Injury to the Cerebrum and Cerebellum - exh5418b
Medical Exhibit
Add to my lightbox
Find More Like This
Post-accident Crush Injuries to the Right Shoulder, Arm and Hand
Post-accident Crush Injuries to the Right Shoulder, Arm and Hand - exh36864a
Medical Exhibit
Add to my lightbox
Find More Like This
Spinal Injuries
Spinal Injuries - exh52619
Medical Exhibit
Add to my lightbox
Find More Like This
Allergic Fungal Sinusitis with Endoscopic Surgical Resection
Allergic Fungal Sinusitis with Endoscopic Surgical Resection - exh66268-nl
Medical Exhibit
Add to my lightbox
Find More Like This
Pancreatic Cancer
Pancreatic Cancer - ANH12065
Medical Animation
Add to my lightbox
Find More Like This
Biology: The Cell: 09: Cell Division - The Cell Cycle
Biology: The Cell: 09: Cell Division - The Cell Cycle - NSV15004
Medical Animation
Add to my lightbox
Find More Like This
What attorneys say about MLA and The Doe Report:
"At 3 PM it hit me--I needed exhibits of a tracheostomy, a coronary artery bypass and a deep vein thrombosis--all in time for a for-trial video deposition the next day. The Doe Report had each exhibit on line. In addition, I ran across an exhibit I hadn't even thought of: reduced ejection fraction after a heart attack. Because this was a video deposition, I could use the e-mail version of the medical exhibit, print it on my color copier, and let the camera zoom in. For $400, less than one blow-up by one of The Doe Report's competitors, I got four first-rate exhibits in less than a day. The Doe Report saved me time and money."

Tracy Kenyon Lischer
Pulley Watson King & Lischer
Durham, NC
www.PWKL.com

"Medical illustrations are essential during trial for any medical malpractice case. The people at MLA have the uncanny ability of creating medical illustrations that simplify the most complex of medical concepts and human anatomy to a lay audience. The exhibits of MLA allow experts to easily describe complex concepts and human anatomy in a manner that could not be done otherwise.

In addition, their custom illustrations show in great detail the extent of injuries suffered and the devastating effects they have had on the client's anatomy. These custom illustration can show, side by side, the body before and after a catastrophic injury. The effect of this juxtaposition is unmatched by any testimony that can be adduced at the time of trial.

Even jurors after trial have commented on the ease with which they grasp medical concepts and anatomy once the MLA exhibits were introduced and used by my experts. Even judges who have "seen it all" are thoroughly impressed by the detail and sophistication of the illustrations.

I would not want to try a case without them."

Lambros Y. Lambrou
McHUGH & LAMBROU, LLP
New York, NY

"I thought you might want to know that after we sent a copy of your illustration to the defendants, with a copy to the insurance company, they increased their offer by an additional million dollars and the case was settled for $1,900,000.00.

I appreciate your help!"

O. Fayrell Furr, Jr.
Furr, Henshaw & Ohanesian
Myrtle Beach, SC
www.scmedicalmalpractice.com

"Medical illustrations are essential evidence in personal injury litigation and MLA is simply the best I've found at producing high-quality illustrations. Your illustrators are not only first-class artists, but creative and responsive. Your turn around time is as good as it gets. My clients have won over $60 million in jury verdicts and I can't recall a case which did not include one of your exhibits. On behalf of those clients, thanks and keep up the great work!"

Kenneth J. Allen
Allen Law Firm
Valparaiso, IN
www.kenallenlaw.com













Awards | Resources | Articles | Become an Affiliate | Free Medical Images | Pregnancy Videos
Credits | Jobs | Help | Medical Legal Blog | Find a Lawyer | Hospital Marketing