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Atherosclerosis - Medical Animation
 
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Item #ANS00260Source #1

Atherosclerosis - Medical Animation
MEDICAL ANIMATION TRANSCRIPT: Atherosclerosis is a life-threatening disease that may have begun to develop during childhood. This condition is a process in which deposits of fatty material, called plaque, build up inside the walls of arteries, reducing or completely blocking blood flow. Although the exact causes of atherosclerosis are not clear, many scientists think it begins with damage to the inner wall of an artery, called the endothelium. Substances traveling in the blood, such as cholesterol, fats and cellular waste products, accumulate inside the damaged area of the arterial wall. Chemical reactions occurring within the buildup of material cause cholesterol molecules to oxidize. This initiates an inflammatory response in which the endothelial cells at the damage site release chemicals that signal a call for help. In response, monocytes from the bloodstream travel to the damage site. Stimulation from oxidized cholesterol converts the monocytes into macrophages. The macrophages eat and digest the cholesterol molecules. As a result of this process, the macrophages change into foam cells, which accumulate to form plaque. As the plaque increases in size, the arterial wall thickens and hardens. At the same time, smooth muscle cells within the arterial wall begin to multiply. Most of the smooth muscle cells move to the surface of the plaque. These cells contribute to the formation of a firm fibrous 'cap' covering the plaque. Eventually, the passageway through the artery narrows enough to reduce blood flow and the amount of oxygen received by the organs it supplies. Over time, the cap may erode and break open, releasing plaque into the bloodstream. The plaque can flow downstream and contribute to the formation of a blood clot, which can stop blood flow. As a result, limited blood supply is available to the areas surrounding the partially blocked artery, degrading and potentially killing the neighboring tissue.

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What attorneys say about MLA and The Doe Report:
"[I] have come to rely upon the Doe Report and your great staff of illustrators for all my medical malpractice cases. … Please know that I enthusiastically recommend you to all my colleagues.

Frank Rothermel
Bernhardt & Rothermel
"It is with great enthusiasm that I recommend Medical Legal Art. We have used their services for three years and always found their professionalism, quality of work, and timely attention to detail to exceed our expectations. We recently settled two complicated catastrophic injury cases. One medical malpractice case involving a spinal abscess settled for 3.75 million and the other involving injuries related to a motor vehicle accident settled for 6.9 million. We consider the artwork provided by MLA to have been invaluable in helping us to successfully conclude these cases.

I highly recommend MLA to anyone seeking high quality, detailed medical legal artwork."

E. Marcus Davis, Esq.
Davis Zipperman, Krischenbaum & Lotito
Atlanta, GA
www.emarcusdavis.com

"Thank you very much for the great work on the medical exhibits. Our trial resulted in a $16 million verdict for a 9 year old boy with catastrophic injuries, and the medical illustrations definitely played key role in the trial."

David Cutt
Brayton Purcell
Salt Lake City, UT

"Our firm was able to settle our case at an all day mediation yesterday and I am confident that the detail and overall appearance of the medical illustrations significantly contributed to the settlement. When we require medical illustrations in the future, I will be sure to contact [MLA]."

Noel Turner, III
Burts, Turner, Rhodes & Thompson
Spartanburg, SC













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